Una D. McCann, M. D.

Associate Professor

Education

Princeton University, BS, 1976-1980, Psychology
Duke University, M.D., 1980-1984, Medicine
Harvard Medical School, Externship, 1982-1983,Endocrinology
Stanford University, Internship, 1984-1985, Psychiatry
Stanford University, Residency, 1985-1988, Psychiatry

Professional Experience

Research Psychiatrist, Continuous Operations Branch, Department of Behavioral Branch, Walter Reed Army Medical Center (WRAIR), 1989-1990
Chief, Continuous Operations Branch, Department of Behavioral Biology, July 1990-1992
Chief, Section on Anxiety and Affective Disorders, Biological Psychiatry Branch, NIHM, July 1992-1999
Associate Professor of Psychiatry, Johns Hopkins University School of Medicine, July 1999-Present

Honors

Summa Cum Laude, Princeton University, 1980
Four-year Academic Scholarship, Princeton University, 1976-1980
Phi Beta Kappa and Sigma Xi Societies, 1980
Sigma Xi Award in Psychology, Princeton University, 1980
Howard Hughes Foundation Student Scholar, Peter Bent Brigham Hospital, 1980
Moos Fellowship for Clinical Research, Stanford University, 1987-1988

Publications

Kaplan MM, McCann UD, Yaskoski KA, Larsen PR, Leonard JL. Anatomical Distribution of Phenolic and Tyrosyl Ring Iodothyronine Deiodinases in the Nervous System of Normal and Hypothyroid Rats. Endocrinology

McCann UD, Agras WS. Successful Treatment of Non-Purging Bulimia with Desipramine: A Double Blind Placebo Controlled Study. American Journal of Psychiatry 1990; 147(11): 1509-1513.

McCann UD, Penetar DM, Belenky GL. Acute Dystonic Reaction in Normal Humans Caused by Catecholamine Depletion. Clinical Neuropharmacology 1990; 13(6): 565-568.

McCann UD, Rossiter EM, King R, Agras WS. Non-Purging Bulimia: a Distinct Subtype of Bulimia Nervosa. International Journal of Eating Disorders 1991:10(6): 679-687.

McCann UD, Penetar DM, Belenky GL. Panic Attacks in Healthy Volunteers Following Alpha-Methyl-Para-Tyrosine Administration. Biological Psychiatry 1991:30:413-416.

McCann UD, Ricaurte GA. Lasting Neuropsychiatric Sequelae of (+) Methylenedioxymethamphetamine ("Ecstasy"). Journal of Clinical Psychopharmacology 1991:11:302-306.

McCann UD, Penetar DL, Shaham et al: Mood Effects of Catecholamine Depletion in Rested and Sleep Deprived Normal Volunteer. Neuropsychopharmacology, 1993:8(4): 345-356.

McCann UD, Penetar DL, Shaham Y, Thorne D, Gillin JC, Sing H, Thomas H, and Belenky G. Sleep Deprivation and Impaired Cognition: The Role of Catecholamines. Biological Psychiatry, 1992:31(11): 1082-1097.

Ricaurte GA, McCann, UD. Neurotoxic Amphetamine Analogs: Effects in Monkeys and Implications for Humans. Annals of the New York Academy of Science, 648:371-382,1992.

McCann UD, Ricaurte GA. Subjective and Neurotoxic Effects of (+) 3,4 Methylenedioxymethamphetamine (MDMA) are Separable: Clinical Evidence. Journal of Clinical Psychopharmacology 13: 214-217, 1993.

Allen R, McCann UD, Ricaurte GA. Sleep in abstinent users of MDMA. Sleep 16:560-564, 1993.

McCann UD, Ricaurte GA. Use and Abuse of Substituted Amphetamines. In: Amphetamine and its Analogs: Neuropsychopharmacology, Toxicology & Abuse, Cho A, Segal D (eds), Academic Press, NY, 1994; 371-381.

McCann UD, Thorne D, Hall T, Sing H, Thomas H, and Belenky G. The Effects of L-DOPA on Alertness and Mood in AMPT-Treated Normal Volunteers: Further Evidence for the Role of Catecholamines in Arousal and Anxiety, Neuropsychopharmacology, 1995; 13(1): 42-52.

McCann UD, Ricaurte GA. On the Neurotoxicity of MDMA and Related Amphetamine Derivatives, J Clinical Psychopharmacology, 1995; 15:295-296.

McCann UD, Slate SO, Geraci M, Uhde TW. Peptides and Anxiety: A Dose-Response Evaluation of Pentagastrin in Healthy Volunteers, Anxiety, 1995; 1:258-267.

McCann UD, Yuan J, Ricaurte GA. Fenfluramine Neurotoxicity and Anorexia: Evidence That the Two Phenomena are Separable, Eur J Pharmacol, 1995; 283:R5-R7.

McCann UD, Yuan J, Hatzidimitriou G, Ricaurte GA: Selective serotonin reuptake inhibitors dissociate fenfluramine’s anorectic and neurotoxic effects. J Pharmacol Exp Ther 281(3), 1997; 1487-1498.

Bolla KI, McCann UD, Ricaurte GA: Impaired memory function in abstinent (+)3,4- methylenedioxymethamphetamine (MDMA) users: Dose-related effects Neurology 51, 1998:1532-1537.

McCann UD, Wong DF, Yokoi F, Villemagne V, Dannals RF, Ricaurte GA: Reduced striatal dopamine transporter density in abstinent methamphetamine and methcathinone users: Evidence from PET studies with [11C]WIN- 35,428. J Neuroscience 18(20), 1998; 8417-8422.

McCann UD, Eligulashvili V, Ricaurte GA: Adverse neuropsychiatric events associated with dexfenfluramine and fenfluramine. Prog Neuro-Psychopharmacol & Biol Psychiat 22: 1998; 1087-1102.

McCann UD, Szabo Z, Scheffel U, Dannals RF, Ricaurte GA: Positron emission tomographic evidence of toxic effect of MDMA ("Ecstasy") on brain serotonin neurons in human beings. Lancet 352: 1433-1437, 1998.

McCann UD, Mertl M, Eligulashvili V, Ricaurte GA: Cognitive performance in MDMA ("Ecstasy") users: A controlled study. Psychopharmacology 143,1999; 417-425.

Hatzidimitriou G, McCann UD, Ricaurte GA: Altered serotonin innervation patterns in the forebrain of monkeys treated with MDMA seven years previously: Factors influencing abnormal recovery. J Neuroscience 191(12), 1999; 5096-5107.


E-mail contact: umccann@jhmi.edu

Updated: 8/5/2000
http://bpru.med.jhu.edu/bio/mccann.html